Cargando…
Long noncoding RNA MALAT1 promotes hepatic steatosis and insulin resistance by increasing nuclear SREBP-1c protein stability
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is implicated in liver cell proliferation. However, its role in hepatic steatosis and insulin resistance remain poorly understood. The aim of this study was to investigate the effects of MALAT1 on hepatic lipid accumulation and its pote...
Autores principales: | Yan, Caifeng, Chen, Jinfeng, Chen, Nuoqi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776244/ https://www.ncbi.nlm.nih.gov/pubmed/26935028 http://dx.doi.org/10.1038/srep22640 |
Ejemplares similares
-
The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis
por: Moon, Young-Ah
Publicado: (2017) -
Impact of silencing hepatic SREBP-1 on insulin signaling
por: Jideonwo, Victoria, et al.
Publicado: (2018) -
GP73 regulates Hepatic Steatosis by enhancing SCAP-SREBPs interaction
por: Yang, Xiaoli, et al.
Publicado: (2017) -
Prevention of Nonalcoholic Hepatic Steatosis by Shenling Baizhu Powder: Involvement of Adiponectin-Induced Inhibition of Hepatic SREBP-1c
por: Tang, Kairui, et al.
Publicado: (2020) -
Inhibition of LXRα/SREBP-1c-Mediated Hepatic Steatosis by Jiang-Zhi Granule
por: Wang, Miao, et al.
Publicado: (2013)