Cargando…

A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke

Stroke represents a global challenge and is a leading cause of permanent disability worldwide. Despite much effort, translation of research findings to clinical benefit has not yet been successful. Failure of neuroprotection trials is considered, in part, due to the low quality of preclinical studie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maysami, Samaneh, Wong, Raymond, Pradillo, Jesus M, Denes, Adam, Dhungana, Hiramani, Malm, Tarja, Koistinaho, Jari, Orset, Cyrille, Rahman, Mahbubur, Rubio, Marina, Schwaninger, Markus, Vivien, Denis, Bath, Philip M, Rothwell, Nancy J, Allan, Stuart M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776311/ https://www.ncbi.nlm.nih.gov/pubmed/26661169 http://dx.doi.org/10.1177/0271678X15606714

Ejemplares similares

Lack of collagen XV is protective after ischemic stroke in mice
por: Dhungana, Hiramani, et al.
Publicado: (2017)

Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 allele
por: Dhungana, Hiramani, et al.
Publicado: (2013)

Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke
por: Kolosowska, Natalia, et al.
Publicado: (2019)

Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation
por: Dhungana, Hiramani, et al.
Publicado: (2017)

Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications
por: Malm, Tarja, et al.
Publicado: (2011)

Glycogen Synthase Kinase-3β: A Mediator of Inflammation in Alzheimer's Disease?
por: Koistinaho, Jari, et al.
Publicado: (2011)

Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta Clearance
por: Malm, Tarja, et al.
Publicado: (2012)

An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo
por: Keuters, Meike Hedwig, et al.
Publicado: (2021)

Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy
por: Huuskonen, Mikko T., et al.
Publicado: (2016)

Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation
por: Kolosowska, Natalia, et al.
Publicado: (2020)

Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway
por: Kanninen, Katja, et al.
Publicado: (2011)

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
por: Martiskainen, Henna, et al.
Publicado: (2017)

Effects of human intravenous immunoglobulin on amyloid pathology and neuroinflammation in a mouse model of Alzheimer’s disease
por: Puli, Lakshman, et al.
Publicado: (2012)

Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice
por: Jäntti, Henna, et al.
Publicado: (2022)

Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis
por: Korhonen, Paula, et al.
Publicado: (2019)

Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro
por: Leow-Dyke, Sophie, et al.
Publicado: (2012)

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia
por: Pradillo, Jesus M., et al.
Publicado: (2017)

Validation of a stroke model in rat compatible with rt-PA-induced thrombolysis: new hope for successful translation to the clinic
por: Arkelius, Kajsa, et al.
Publicado: (2020)

Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR‐127 in aged animals
por: Loppi, Sanna, et al.
Publicado: (2020)

Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease
por: Magga, Johanna, et al.
Publicado: (2010)

3D transcranial ultrasound localization microscopy for discrimination between ischemic and hemorrhagic stroke in early phase
por: Chavignon, Arthur, et al.
Publicado: (2022)

Publisher Correction: 3D transcranial ultrasound localization microscopy for discrimination between ischemic and hemorrhagic stroke in early phase
por: Chavignon, Arthur, et al.
Publicado: (2022)

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice
por: Puris, Elena, et al.
Publicado: (2021)

Production of monocytic cells from bone marrow stem cells: therapeutic usage in Alzheimer’s disease
por: Magga, Johanna, et al.
Publicado: (2012)

Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer’s Disease
por: Gynther, Mikko, et al.
Publicado: (2022)

ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
por: Lemarchant, Sighild, et al.
Publicado: (2016)

Erratum to: ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
por: Lemarchant, Sighild, et al.
Publicado: (2016)

Aβ and Inflammatory Stimulus Activate Diverse Signaling Pathways in Monocytic Cells: Implications in Retaining Phagocytosis in Aβ-Laden Environment
por: Savchenko, Ekaterina, et al.
Publicado: (2016)

Combination treatment with U0126 and rt-PA prevents adverse effects of the delayed rt-PA treatment after acute ischemic stroke
por: Orset, Cyrille, et al.
Publicado: (2021)

Surgical manipulation compromises leukocyte mobilization responses and inflammation after experimental cerebral ischemia in mice
por: Denes, Adam, et al.
Publicado: (2014)

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
por: Liddell, Jeffrey R., et al.
Publicado: (2016)

Activation of P2X7 Receptors in Peritoneal and Meningeal Mast Cells Detected by Uptake of Organic Dyes: Possible Purinergic Triggers of Neuroinflammation in Meninges
por: Nurkhametova, Dilyara, et al.
Publicado: (2019)

Retinal Degeneration In A Mouse Model Of CLN5 Disease Is Associated With Compromised Autophagy
por: Leinonen, Henri, et al.
Publicado: (2017)

Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis
por: Pollari, Eveliina, et al.
Publicado: (2011)

Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation
por: Byts, Nadiya, et al.
Publicado: (2022)

Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology
por: Greenhalgh, Andrew D., et al.
Publicado: (2012)

Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons
por: Wong, Raymond, et al.
Publicado: (2019)

Emerging Role of miR-21-5p in Neuron–Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer’s Disease
por: Garcia, Gonçalo, et al.
Publicado: (2022)

Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice
por: Denes, Adam, et al.
Publicado: (2013)

Interleukin Expression after Injury and the Effects of Interleukin-1 Receptor Antagonist
por: Chamberlain, Connie S., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_762os1qmva4pglce40gnsasi3g