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Knockdown of SALL4 inhibits the proliferation and reverses the resistance of MCF-7/ADR cells to doxorubicin hydrochloride
BACKGROUND: Breast cancer is the most frequent malignancy in women and drug resistance is the major obstacle for its successful chemotherapy. In the present study, we analyzed the involvement of an oncofetal gene, sal-like 4 (SALL4), in the tumor proliferation and drug resistance of human breast can...
Autores principales: | Chen, Yuan-Yuan, Li, Zhi-Zhen, Ye, Yuan-Yuan, Xu, Feng, Niu, Rui-Jie, Zhang, Hong-Chen, Zhang, Yi-Jian, Liu, Ying-Bin, Han, Bao-San |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776391/ https://www.ncbi.nlm.nih.gov/pubmed/26935744 http://dx.doi.org/10.1186/s12867-016-0055-y |
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