Cargando…

Enhancing full-length antibody production by signal peptide engineering

BACKGROUND: Protein secretion to the periplasm of Escherichia coli offers an attractive route for producing heterologous proteins including antibodies. In this approach, a signal peptide is fused to the N-terminus of the heterologous protein. The signal peptide mediates translocation of the heterolo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yizhou, Liu, Peter, Gan, Yutian, Sandoval, Wendy, Katakam, Anand Kumar, Reichelt, Mike, Rangell, Linda, Reilly, Dorothea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776426/ https://www.ncbi.nlm.nih.gov/pubmed/26935575 http://dx.doi.org/10.1186/s12934-016-0445-3

Ejemplares similares

Efficient expression of full-length antibodies in the cytoplasm of engineered bacteria
por: Robinson, Michael-Paul, et al.
Publicado: (2015)

YEAST SURFACE DISPLAY OF FULL-LENGTH IGG FOR ENGINEERING MONOCLONAL AND BISPECIFIC ANTIBODIES
por: Jiang, Youwei
Publicado: (2023)

Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation
por: Rashid, Md Harunur
Publicado: (2022)

Identification and Quantification of Oxidation Products in Full-Length Biotherapeutic Antibodies by NMR Spectroscopy
por: Hinterholzer, Arthur, et al.
Publicado: (2020)

Structure of Full-length Drosophila Cryptochrome
por: Zoltowski, Brian D., et al.
Publicado: (2011)

Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity
por: Shatz, Whitney, et al.
Publicado: (2013)

Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii
por: Huang, Ke-Jung, et al.
Publicado: (2022)

High cell-surface density of HER2 deforms cell membranes
por: Chung, Inhee, et al.
Publicado: (2016)

Antibodies to Full-Length Agrin Protein in Chinese Patients With Myasthenia Gravis
por: Wang, Shumin, et al.
Publicado: (2021)

Structural Characterization of the Full-Length Anti-CD20 Antibody Rituximab
por: Belviso, Benny Danilo, et al.
Publicado: (2022)

Structure of full-length TSH receptor in complex with antibody K1-70™
por: Núñez Miguel, Ricardo, et al.
Publicado: (2022)

Nuclear processing of nascent transcripts determines synthesis of full-length proteins and antigenic peptides
por: Martins, Rodrigo Prado, et al.
Publicado: (2019)

High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies
por: Lombana, T. Noelle, et al.
Publicado: (2018)

Production, Purification and Characterization of Recombinant, Full-Length Human Claudin-1
por: Bonander, Nicklas, et al.
Publicado: (2013)

Peptidoglycan Association of Murein Lipoprotein Is Required for KpsD-Dependent Group 2 Capsular Polysaccharide Expression and Serum Resistance in a Uropathogenic Escherichia coli Isolate
por: Diao, Jingyu, et al.
Publicado: (2017)

Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab
por: Xing, Man, et al.
Publicado: (2016)

The mosaic puzzle of the therapeutic monoclonal antibodies and antibody fragments - A modular transition from full-length immunoglobulins to antibody mimetics
por: Khatib, Sami El, et al.
Publicado: (2022)

Fluorescent Affibody Peptide Penetration in Glioma Margin Is Superior to Full Antibody
por: Sexton, Kristian, et al.
Publicado: (2013)

Both Full-Length and Protease-Cleaved Products of Osteopontin Are Elevated in Infectious Diseases
por: Hattori, Toshio, et al.
Publicado: (2021)

Production of an Active, Human Membrane Protein in Saccharomyces cerevisiae: Full-Length FICD
por: Virolainen, Minttu S., et al.
Publicado: (2022)

High Avidity Antibodies to Full-Length VAR2CSA Correlate with Absence of Placental Malaria
por: Tutterrow, Yeung Lo, et al.
Publicado: (2012)

REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells
por: Rhiel, Laura, et al.
Publicado: (2014)

Functional heterologous expression of an engineered full length CipA from Clostridium thermocellum in Thermoanaerobacterium saccharolyticum
por: Currie, Devin H, et al.
Publicado: (2013)

A Novel Strategy to Engineer Pre-Vascularized Full-Length Dental Pulp-like Tissue Constructs
por: Athirasala, Avathamsa, et al.
Publicado: (2017)

Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues
por: Bremner, Samantha B, et al.
Publicado: (2022)

Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein
por: Das, Debanu, et al.
Publicado: (2011)

Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology
por: Galati, Clelia, et al.
Publicado: (2017)

Detection and Full-Length Genome Characterization of Novel Canine Vesiviruses
por: Martella, Vito, et al.
Publicado: (2015)

Scalable Production in Human Cells and Biochemical Characterization of Full-Length Normal and Mutant Huntingtin
por: Huang, Bin, et al.
Publicado: (2015)

Full-length transcriptome analysis of shade-induced promotion of tuber production in Pinellia ternata
por: Xue, Tao, et al.
Publicado: (2019)

Optimized Expression of Full-Length IgG1 Antibody in a Common E. coli Strain
por: Chan, Conrad En Zuo, et al.
Publicado: (2010)

Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers
por: Fodjo, Barriere A. Y., et al.
Publicado: (2016)

An oncolytic virus expressing a full-length antibody enhances antitumor innate immune response to glioblastoma
por: Xu, Bo, et al.
Publicado: (2021)

Isolation of full-length IgG antibodies from combinatorial libraries expressed in the cytoplasm of Escherichia coli
por: Robinson, Michael-Paul, et al.
Publicado: (2023)

Characterization of full-length p53 aggregates and their kinetics of formation
por: Julian, Linda, et al.
Publicado: (2022)

Antibodies to a Full-Length VAR2CSA Immunogen Are Broadly Strain-Transcendent but Do Not Cross-Inhibit Different Placental-Type Parasite Isolates
por: Avril, Marion, et al.
Publicado: (2011)

Full-length genome sequence of Ntaya virus
por: Dilcher, Meik, et al.
Publicado: (2012)

Conformational states of the full-length glucagon receptor
por: Yang, Linlin, et al.
Publicado: (2015)

Management of full-length complete ureteral avulsion
por: Tang, Kaifa, et al.
Publicado: (2016)

Structure of full-length human TRPM4
por: Duan, Jingjing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ah7pmfm1lk2pk5pf1vc13cmmef