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Induction of mitochondrial reactive oxygen species production by GSH mediated S-glutathionylation of 2-oxoglutarate dehydrogenase

2-Oxoglutarate dehydrogenase (Ogdh) is an important mitochondria redox sensor that can undergo S-glutathionylation following an increase in H(2)O(2) levels. Although S-glutathionylation is required to protect Ogdh from irreversible oxidation while simultaneously modulating its activity it remains un...

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Detalles Bibliográficos
Autores principales:	Mailloux, Ryan J., Craig Ayre, D., Christian, Sherri L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776629/ https://www.ncbi.nlm.nih.gov/pubmed/26928132 http://dx.doi.org/10.1016/j.redox.2016.02.002

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