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Computed Tomographic Pattern of Physiological Intracranial Calcifications in a City in Central Africa

OBJECTIVE: Intracranial calcifications underlie certain brain diseases which may be de novo or systemic. But calclfications un-connected to pathologies are classified physiological. AIM: To evaluate physiological intracranial calcifications in Douala with establishment of earliest age range of detec...

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Detalles Bibliográficos
Autores principales: Uduma, Uduma Felix, Pius, Fokam, Mathieu, Motah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Canadian Center of Science and Education 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777028/
https://www.ncbi.nlm.nih.gov/pubmed/22980109
http://dx.doi.org/10.5539/gjhs.v4n1p184
Descripción
Sumario:OBJECTIVE: Intracranial calcifications underlie certain brain diseases which may be de novo or systemic. But calclfications un-connected to pathologies are classified physiological. AIM: To evaluate physiological intracranial calcifications in Douala with establishment of earliest age range of detection. MATERIALS AND METHODS: Prospective study of brain computed tomograms was done from April to October 2009 using Schumadzu CT Scan machine. Axial, reconstructed and bone window images as well Hounsfield unit measurements were used for final evaluations. Results were analysed with SSPS 3. RESULTS: 132 patients with 75 males and 57 females were studied and 163 separate calcifications were identified due to co-existent calcifications. The highest calcification was in choroid plexi, constituiting 56.82% of the studied population. This was followed by pineal gland. Both were commonly co-existent with advancing age. These calcifications were first seen at 10-19years. No type of physiological intracranial calcification was seen below age 10. The least calcification of 0.76% of population was in dentate nucleus. CONCLUSION: No intra-cranial physiological calcifications started earlier than 9years in Douala, a city in Cameroon, Central Africa.