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A Computational Approach to Estimating Nondisjunction Frequency in Saccharomyces cerevisiae

Errors segregating homologous chromosomes during meiosis result in aneuploid gametes and are the largest contributing factor to birth defects and spontaneous abortions in humans. Saccharomyces cerevisiae has long served as a model organism for studying the gene network supporting normal chromosome s...

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Detalles Bibliográficos
Autores principales: Chu, Daniel B., Burgess, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777129/
https://www.ncbi.nlm.nih.gov/pubmed/26747203
http://dx.doi.org/10.1534/g3.115.024380