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miRNA‐27b levels are associated with CYP3A activity in vitro and in vivo
Previous in vitro studies have shown that microRNA‐27b (miR‐27b) may regulate mRNA levels of CYP3A4, vitamin D receptor (VDR), and Peroxisome proliferator‐activated receptor α (PPAR α) as well as CYP3A4 protein expression and activity. In vitro studies have also shown that vitamin D may affect the e...
Autores principales: | Ekström, Lena, Skilving, Ilona, Ovesjö, Marie‐Louise, Aklillu, Eleni, Nylén, Hanna, Rane, Anders, Diczfalusy, Ulf, Björkhem‐Bergman, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777245/ https://www.ncbi.nlm.nih.gov/pubmed/27022466 http://dx.doi.org/10.1002/prp2.192 |
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