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Claudin‐4 binder C‐CPE 194 enhances effects of anticancer agents on pancreatic cancer cell lines via a MAPK pathway

The C‐terminal fragment of Clostridium perfringens enterotoxin (C‐CPE) modulates the tight junction protein claudin and disrupts the tight junctional barrier. It also can enhance the effectiveness of anticancer agents. However, the detailed mechanisms of the effects of C‐CPE remain unclear in both n...

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Detalles Bibliográficos
Autores principales: Kono, Tsuyoshi, Kondoh, Masuo, Kyuno, Daisuke, Ito, Tatsuya, Kimura, Yasutoshi, Imamura, Masafumi, Kohno, Takayuki, Konno, Takumi, Furuhata, Tomohisa, Sawada, Norimasa, Hirata, Koichi, Kojima, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777248/
https://www.ncbi.nlm.nih.gov/pubmed/27022469
http://dx.doi.org/10.1002/prp2.196