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Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway

OBJECTIVE: To investigate the effects of papaverine (PAP) on lipopolysaccharide (LPS)-induced microglial activation and its possible mechanisms. MATERIALS AND METHODS: BV2 microglial cells were first pretreated with PAP (0, 0.4, 2, 10, and 50 μg/mL) and then received LPS stimulation. Transcription a...

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Detalles Bibliográficos
Autores principales:	Dang, Yalong, Mu, Yalin, Wang, Kun, Xu, Ke, Yang, Jing, Zhu, Yu, Luo, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777259/ https://www.ncbi.nlm.nih.gov/pubmed/27013863 http://dx.doi.org/10.2147/DDDT.S97380

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