Alpha8 Integrin (Itga8) Signalling Attenuates Chronic Renal Interstitial Fibrosis by Reducing Fibroblast Activation, Not by Interfering with Regulation of Cell Turnover

The α8 integrin (Itga8) chain contributes to the regulation of cell proliferation and apoptosis in renal glomerular cells. In unilateral ureteral obstruction Itga8 is de novo expressed in the tubulointerstitium and a deficiency of Itga8 results in more severe renal fibrosis after unilateral ureteral...

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Detalles Bibliográficos
Autores principales: Marek, Ines, Lichtneger, Till, Cordasic, Nada, Hilgers, Karl F., Volkert, Gudrun, Fahlbusch, Fabian, Rascher, Wolfgang, Hartner, Andrea, Menendez-Castro, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777439/
https://www.ncbi.nlm.nih.gov/pubmed/26938996
http://dx.doi.org/10.1371/journal.pone.0150471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777439/
https://www.ncbi.nlm.nih.gov/pubmed/26938996
http://dx.doi.org/10.1371/journal.pone.0150471

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