Cargando…
Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication
Allostery is one of the pervasive mechanisms through which proteins in living systems carry out enzymatic activity, cell signaling, and metabolism control. Effective modeling of the protein function regulation requires a synthesis of the thermodynamic and structural views of allostery. We present he...
Autores principales: | Guarnera, Enrico, Berezovsky, Igor N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777440/ https://www.ncbi.nlm.nih.gov/pubmed/26939022 http://dx.doi.org/10.1371/journal.pcbi.1004678 |
Ejemplares similares
-
Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response
por: Tee, Wei-Ven, et al.
Publicado: (2018) -
Disorder driven allosteric control of protein activity
por: Tee, Wei-Ven, et al.
Publicado: (2020) -
AlloSigMA 2: paving the way to designing allosteric effectors and to exploring allosteric effects of mutations
por: Tan, Zhen Wah, et al.
Publicado: (2020) -
AlloMAPS 2: allosteric fingerprints of the AlphaFold and Pfam-trRosetta predicted structures for engineering and design
por: Tan, Zhen Wah, et al.
Publicado: (2022) -
Coherent Conformational Degrees of Freedom as a Structural Basis for Allosteric Communication
por: Mitternacht, Simon, et al.
Publicado: (2011)