Cargando…

Development of new 5-(chromene-3-yl)methylene-2,4-thiazolidinediones as antimicrobial agents

BACKGROUND AND AIMS: In the context of the increasing phenomenon of microbial resistance to usual drugs, the development of new treatment strategies and new therapeutic protocols is a constant need. Thiazolidinedione and chromone represent two important scaffolds in medicinal chemistry due to their...

Descripción completa

Detalles Bibliográficos
Autores principales:	NASTASĂ, CRISTINA MARIANA, DUMA, MIHAELA, PÎRNĂU, ADRIAN, VLASE, LAURIAN, TIPERCIUC, BRÎNDUŞA, ONIGA, OVIDIU
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Iuliu Hatieganu University of Medicine and Pharmacy 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777455/ https://www.ncbi.nlm.nih.gov/pubmed/27004035 http://dx.doi.org/10.15386/cjmed-509

Ejemplares similares

5-Arylidene(chromenyl-methylene)-thiazolidinediones: Potential New Agents against Mutant Oncoproteins K-Ras, N-Ras and B-Raf in Colorectal Cancer and Melanoma
por: Nastasă, Cristina, et al.
Publicado: (2019)

Synthesis of New Phenolic Derivatives of Quinazolin-4(3H)-One as Potential Antioxidant Agents—In Vitro Evaluation and Quantum Studies
por: Pele, Raluca, et al.
Publicado: (2022)

New N-(oxazolylmethyl)-thiazolidinedione Active against Candida albicans Biofilm: Potential Als Proteins Inhibitors
por: Marc, Gabriel, et al.
Publicado: (2018)

New Hydrazones Bearing Thiazole Scaffold: Synthesis, Characterization, Antimicrobial, and Antioxidant Investigation
por: Nastasă, Cristina, et al.
Publicado: (2015)

Design, Synthesis and Antifungal Activity Evaluation of New Thiazolin-4-ones as Potential Lanosterol 14α-Demethylase Inhibitors
por: Stana, Anca, et al.
Publicado: (2017)

A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies
por: Borcea, Anca-Maria, et al.
Publicado: (2019)

Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents
por: Marc, Gabriel, et al.
Publicado: (2019)

Stachys Species: Comparative Evaluation of Phenolic Profile and Antimicrobial and Antioxidant Potential
por: Benedec, Daniela, et al.
Publicado: (2023)

New Phenolic Derivatives of Thiazolidine-2,4-dione with Antioxidant and Antiradical Properties: Synthesis, Characterization, In Vitro Evaluation, and Quantum Studies
por: Marc, Gabriel, et al.
Publicado: (2019)

Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin
por: Pricopie, Andreea-Iulia, et al.
Publicado: (2019)

Antioxidant and Cytotoxic Activity of New Polyphenolic Derivatives of Quinazolin-4(3H)-one: Synthesis and In Vitro Activities Evaluation
por: Pele, Raluca, et al.
Publicado: (2022)

Achillea schurii Flowers: Chemical, Antioxidant, and Antimicrobial Investigations
por: Benedec, Daniela, et al.
Publicado: (2016)

Synthesis, lipophilicity and antimicrobial activity evaluation of some new thiazolyl-oxadiazolines
por: STOICA, CRISTINA IOANA, et al.
Publicado: (2015)

Sources for developing new medicinal products: biochemical investigations on alcoholic extracts obtained from aerial parts of some Romanian Amaryllidaceae species
por: Benedec, Daniela, et al.
Publicado: (2018)

Antioxidant Activity Evaluation and Assessment of the Binding Affinity to HSA of a New Catechol Hydrazinyl-Thiazole Derivative
por: Mic, Mihaela, et al.
Publicado: (2022)

Antibacterial Evaluation and Virtual Screening of New Thiazolyl-Triazole Schiff Bases as Potential DNA-Gyrase Inhibitors
por: Nastasă, Cristina, et al.
Publicado: (2018)

Study of the Relationships between the Structure, Lipophilicity and Biological Activity of Some Thiazolyl-carbonyl-thiosemicarbazides and Thiazolyl-azoles
por: Tamaian, Radu, et al.
Publicado: (2015)

Phenolic Thiazoles with Antioxidant and Antiradical Activity. Synthesis, In Vitro Evaluation, Toxicity, Electrochemical Behavior, Quantum Studies and Antimicrobial Screening
por: Marc, Gabriel, et al.
Publicado: (2021)

Novel 2,4-Disubstituted-1,3-Thiazole Derivatives: Synthesis, Anti-Candida Activity Evaluation and Interaction with Bovine Serum Albumine
por: Pricopie, Andreea-Iulia, et al.
Publicado: (2020)

New Thiazolyl-triazole Schiff Bases: Synthesis and Evaluation of the Anti-Candida Potential
por: Stana, Anca, et al.
Publicado: (2016)

Discovery of New Hydrazone-Thiazole Polyphenolic Antioxidants through Computer-Aided Design and In Vitro Experimental Validation
por: Marc, Gabriel, et al.
Publicado: (2023)

Polyphenolic Composition, Antioxidant and Antibacterial Activities for Two Romanian Subspecies of Achillea distans Waldst. et Kit. ex Willd
por: Benedec, Daniela, et al.
Publicado: (2013)

Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitors
por: Stana, Anca, et al.
Publicado: (2019)

Inclusion of a Catechol-Derived Hydrazinyl-Thiazole (CHT) in β-Cyclodextrin Nanocavity and Its Effect on Antioxidant Activity: A Calorimetric, Spectroscopic and Molecular Docking Approach
por: Mic, Mihaela, et al.
Publicado: (2023)

Solidago graminifolia L. Salisb. (Asteraceae) as a Valuable Source of Bioactive Polyphenols: HPLC Profile, In Vitro Antioxidant and Antimicrobial Potential
por: Toiu, Anca, et al.
Publicado: (2019)

New Approaches on the Anti-Inflammatory and Cardioprotective Properties of Taraxacum officinale Tincture
por: Epure, Alexandra, et al.
Publicado: (2023)

Phytochemical Composition, Antioxidant, Antimicrobial and in Vivo Anti-inflammatory Activity of Traditionally Used Romanian Ajuga laxmannii (Murray) Benth. (“Nobleman’s Beard” – Barba Împăratului)
por: Toiu, Anca, et al.
Publicado: (2018)

Recent Pharmacological Developments on Rhodanines and 2,4-Thiazolidinediones
por: Bhatti, Ravinder Singh, et al.
Publicado: (2013)

Comparative Phytochemical Profile, Antioxidant, Antimicrobial and In Vivo Anti-Inflammatory Activity of Different Extracts of Traditionally Used Romanian Ajuga genevensis L. and A. reptans L. (Lamiaceae)
por: Toiu, Anca, et al.
Publicado: (2019)

Effects of Thiazolidinedione and New Antidiabetic Agents on Stroke
por: Ahn, Chang Ho, et al.
Publicado: (2019)

Phytochemical Characterization of Veronica officinalis L., V. teucrium L. and V. orchidea Crantz from Romania and Their Antioxidant and Antimicrobial Properties
por: Mocan, Andrei, et al.
Publicado: (2015)

Indole and 2,4-Thiazolidinedione conjugates as potential anticancer modulators
por: Corigliano, Domenica M., et al.
Publicado: (2018)

New 2-Phenylthiazoles as Potential Sortase A Inhibitors: Synthesis, Biological Evaluation and Molecular Docking
por: Oniga, Smaranda Dafina, et al.
Publicado: (2017)

Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein
por: Ruggiero, Dafne, et al.
Publicado: (2022)

Design of Novel 4-Hydroxy-chromene-2-one Derivatives as Antimicrobial Agents
por: Mladenović, Milan, et al.
Publicado: (2010)

3,3′-[(4-Nitrophenyl)methylene]bis(4-hydroxy-2H-chromen-2-one)
por: Ravikumar, N., et al.
Publicado: (2012)

Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents
por: Afifi, Tarek H., et al.
Publicado: (2017)

1-[(Bromomethyl)(phenyl)methylene]-2-(2,4-dinitrophenyl)hydrazine
por: Salhin, Abdussalam, et al.
Publicado: (2009)

Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds
por: Gaspar, Alexandra, et al.
Publicado: (2019)

3-[(4-Oxo-4H-thiochromen-3-yl)methyl]-4H-thiochromen-4-one
por: Somasundaram, M., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_agsdlffr00ubiscc4mqass8g7m