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Primary Ovarian Insufficiency Induced by Fanconi Anemia E Mutation in a Mouse Model
In most cases of primary ovarian insufficiency (POI), the cause of the depletion of ovarian follicles is unknown. Fanconi anemia (FA) proteins are known to play important roles in follicular development. Using random insertional mutagenesis with a lentiviral transgene, we identified a family with re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777492/ https://www.ncbi.nlm.nih.gov/pubmed/26939056 http://dx.doi.org/10.1371/journal.pone.0144285 |