Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells

Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly secreted by hepatocytes. However, its role in liver injury and fibrogenesis has not been elucidated so far. In this study, we determined the effects of SAA on hepatic stellate cells (HSCs), the main f...

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Detalles Bibliográficos
Autores principales: Siegmund, Sören V., Schlosser, Monika, Schildberg, Frank A., Seki, Ekihiro, De Minicis, Samuele, Uchinami, Hiroshi, Kuntzen, Christian, Knolle, Percy A., Strassburg, Christian P., Schwabe, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777566/
https://www.ncbi.nlm.nih.gov/pubmed/26937641
http://dx.doi.org/10.1371/journal.pone.0150893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777566/
https://www.ncbi.nlm.nih.gov/pubmed/26937641
http://dx.doi.org/10.1371/journal.pone.0150893

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