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NAD(+)-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus

A global increase in invasive infections due to group A Streptococcus (S. pyogenes or GAS) has been observed since the 1980s, associated with emergence of a clonal group of strains of the M1T1 serotype. Among other virulence attributes, the M1T1 clone secretes NAD(+)-glycohydrolase (NADase). When GA...

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Detalles Bibliográficos
Autores principales:	Sharma, Onkar, O’Seaghdha, Maghnus, Velarde, Jorge J., Wessels, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777570/ https://www.ncbi.nlm.nih.gov/pubmed/26938870 http://dx.doi.org/10.1371/journal.ppat.1005468

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