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Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway

Aberrant Wnt signaling pathway is associated with a wide array of tumor types and plays an important role in the drug resistance of cancer stem cells (CSCs). To explore the effects and mechanism of WNT signaling pathway inhibitor XAV939 on drug resistance in colon cancer cells, the colon cancer cell...

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Detalles Bibliográficos
Autores principales: WU, XUEFANG, LUO, FENG, LI, JINBANG, ZHONG, XUEYUN, LIU, KUNPING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777596/
https://www.ncbi.nlm.nih.gov/pubmed/26820603
http://dx.doi.org/10.3892/ijo.2016.3360