Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil

Chemokine-mediated activation of G protein-coupled receptors CXCR1/2 promotes tumor growth, invasion, inflammation and metastasis. Repertaxin, a CXCR1/2 small-molecule inhibitor, has been shown to attenuate many of these tumor-associated processes. The present study aimed to investigate the effects...

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Detalles Bibliográficos
Autores principales: WANG, JUNPU, HU, WANMING, WANG, KUANSONG, YU, JUN, LUO, BAIHUA, LUO, GENGQIU, WANG, WEIYUAN, WANG, HUILING, LI, JINGHE, WEN, JIFANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777600/
https://www.ncbi.nlm.nih.gov/pubmed/26847910
http://dx.doi.org/10.3892/ijo.2016.3371

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