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EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis

PRDM1/Blimp1, a master regulator of B-cell terminal differentiation, has been identified as a tumor suppressor gene in aggressive lymphomas, including diffuse large B-cell lymphoma (DLBCL). It has been shown in DLBCL and Hodgkin lymphoma that PRDM1 is downregulated by cellular microRNAs. In this stu...

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Detalles Bibliográficos
Autores principales:	Ma, J, Nie, K, Redmond, D, Liu, Y, Elemento, O, Knowles, D M, Tam, W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777778/ https://www.ncbi.nlm.nih.gov/pubmed/26530011 http://dx.doi.org/10.1038/leu.2015.285

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