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Evaluation of pesticide residues in human blood samples from Punjab (India)
AIM: The present study was undertaken to estimate the current status of residues of organochlorine pesticides (OCPs), organophosphates (OPs) and synthetic pyrethroids (SPs) pesticides in human blood. MATERIALS AND METHODS: Human blood samples were analyzed by gas chromatography and confirmed by gas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Veterinary World
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777814/ https://www.ncbi.nlm.nih.gov/pubmed/27046999 http://dx.doi.org/10.14202/vetworld.2015.66-71 |
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author | Bedi, Jasbir Singh Gill, J. P. S. Kaur, P. Sharma, A. Aulakh, R. S. |
author_facet | Bedi, Jasbir Singh Gill, J. P. S. Kaur, P. Sharma, A. Aulakh, R. S. |
author_sort | Bedi, Jasbir Singh |
collection | PubMed |
description | AIM: The present study was undertaken to estimate the current status of residues of organochlorine pesticides (OCPs), organophosphates (OPs) and synthetic pyrethroids (SPs) pesticides in human blood. MATERIALS AND METHODS: Human blood samples were analyzed by gas chromatography and confirmed by gas chromatography-mass spectrometry in selective ion monitoring mode. RESULTS: The gas chromatographic analysis of human blood samples collected from Punjab revealed the presence of p,p’-dichlorodiphenyl dichloroethylene (DDE), p,p’ dichlorodiphenyl dichloroethane (DDD), o,p’ DDE and β-endosulfan at mean levels of 15.26, 2.71, 5.62 and 4.02 ng/ml, respectively. p,p’ DDE residue was observed in 18.0% blood samples, and it contributes 55% of the total pesticide burden in human blood. The difference of total dichlorordiphenyl trichloroethane (DDT) between different age groups of humans was found to be statistically significant (p<0.05). The difference of DDT and endosulfan between dietary habits, gender and spraying of pesticides was found statistically non-significant, however endosulfan residues were observed only in pesticide sprayer’s population. CONCLUSION: Occurrence of p,p’ DDE, p,p’ DDD, o,p’ DDE in human blood indicated restricted use of DDT. However, presence of endosulfan residues in occupationally exposed population is a matter of public health concern. |
format | Online Article Text |
id | pubmed-4777814 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Veterinary World |
record_format | MEDLINE/PubMed |
spelling | pubmed-47778142016-04-04 Evaluation of pesticide residues in human blood samples from Punjab (India) Bedi, Jasbir Singh Gill, J. P. S. Kaur, P. Sharma, A. Aulakh, R. S. Vet World Research Article AIM: The present study was undertaken to estimate the current status of residues of organochlorine pesticides (OCPs), organophosphates (OPs) and synthetic pyrethroids (SPs) pesticides in human blood. MATERIALS AND METHODS: Human blood samples were analyzed by gas chromatography and confirmed by gas chromatography-mass spectrometry in selective ion monitoring mode. RESULTS: The gas chromatographic analysis of human blood samples collected from Punjab revealed the presence of p,p’-dichlorodiphenyl dichloroethylene (DDE), p,p’ dichlorodiphenyl dichloroethane (DDD), o,p’ DDE and β-endosulfan at mean levels of 15.26, 2.71, 5.62 and 4.02 ng/ml, respectively. p,p’ DDE residue was observed in 18.0% blood samples, and it contributes 55% of the total pesticide burden in human blood. The difference of total dichlorordiphenyl trichloroethane (DDT) between different age groups of humans was found to be statistically significant (p<0.05). The difference of DDT and endosulfan between dietary habits, gender and spraying of pesticides was found statistically non-significant, however endosulfan residues were observed only in pesticide sprayer’s population. CONCLUSION: Occurrence of p,p’ DDE, p,p’ DDD, o,p’ DDE in human blood indicated restricted use of DDT. However, presence of endosulfan residues in occupationally exposed population is a matter of public health concern. Veterinary World 2015-01 2015-01-21 /pmc/articles/PMC4777814/ /pubmed/27046999 http://dx.doi.org/10.14202/vetworld.2015.66-71 Text en Copyright: The authors. http://creativecommons.org/licenses/by/2.0 This article is an open access article licensed under the terms of the Creative Commons Attributin License (http://creative commons.org/licenses/by/2.0) which permits unrestricted use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Research Article Bedi, Jasbir Singh Gill, J. P. S. Kaur, P. Sharma, A. Aulakh, R. S. Evaluation of pesticide residues in human blood samples from Punjab (India) |
title | Evaluation of pesticide residues in human blood samples from Punjab (India) |
title_full | Evaluation of pesticide residues in human blood samples from Punjab (India) |
title_fullStr | Evaluation of pesticide residues in human blood samples from Punjab (India) |
title_full_unstemmed | Evaluation of pesticide residues in human blood samples from Punjab (India) |
title_short | Evaluation of pesticide residues in human blood samples from Punjab (India) |
title_sort | evaluation of pesticide residues in human blood samples from punjab (india) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777814/ https://www.ncbi.nlm.nih.gov/pubmed/27046999 http://dx.doi.org/10.14202/vetworld.2015.66-71 |
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