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Regulation of Transient Site-specific Copy Gain by MicroRNA

Intra-tumor copy number heterogeneity is commonly observed in cancer; however, the molecular mechanisms that contribute to heterogeneity remain poorly understood. Up-regulation of the histone demethylase KDM4A promotes transient site-specific copy gain (TSSG) in cells; therefore, uncovering how KDM4...

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Detalles Bibliográficos
Autores principales:	Black, Joshua C., Zhang, Hailei, Kim, Jaegil, Getz, Gad, Whetstine, Johnathan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777823/ https://www.ncbi.nlm.nih.gov/pubmed/26755726 http://dx.doi.org/10.1074/jbc.M115.711648

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