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An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
Tendinous and subcutaneous xanthomas are nodular deposits of lipid-filled macrophages, which commonly form on the Achilles tendon, hands, feet, elbows, and knees. These nodules are frequently associated with familial hyperlipidemia, a group of diseases involving impaired cholesterol metabolism, and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777906/ https://www.ncbi.nlm.nih.gov/pubmed/26955329 http://dx.doi.org/10.1159/000441711 |
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author | Bermudez, Eduardo B. Storey, Leslie Mayo, Sheila Simpson, Gregory |
author_facet | Bermudez, Eduardo B. Storey, Leslie Mayo, Sheila Simpson, Gregory |
author_sort | Bermudez, Eduardo B. |
collection | PubMed |
description | Tendinous and subcutaneous xanthomas are nodular deposits of lipid-filled macrophages, which commonly form on the Achilles tendon, hands, feet, elbows, and knees. These nodules are frequently associated with familial hyperlipidemia, a group of diseases involving impaired cholesterol metabolism, and the accelerated development of atherosclerotic plaques. Since xanthomas may precede the diagnosis of hyperlipidemia, early identification can lead to preventative treatment that reduces the risk and morbidity of cardiovascular disease, including myocardial infarction. This case report presents a 43-year-old African-American male with multiple xanthomas involving the Achilles tendon, soles, hands, knees, elbows, and is associated with the unusual involvement of the ear. |
format | Online Article Text |
id | pubmed-4777906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-47779062016-03-07 An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears Bermudez, Eduardo B. Storey, Leslie Mayo, Sheila Simpson, Gregory Case Rep Dermatol Published online: November, 2015 Tendinous and subcutaneous xanthomas are nodular deposits of lipid-filled macrophages, which commonly form on the Achilles tendon, hands, feet, elbows, and knees. These nodules are frequently associated with familial hyperlipidemia, a group of diseases involving impaired cholesterol metabolism, and the accelerated development of atherosclerotic plaques. Since xanthomas may precede the diagnosis of hyperlipidemia, early identification can lead to preventative treatment that reduces the risk and morbidity of cardiovascular disease, including myocardial infarction. This case report presents a 43-year-old African-American male with multiple xanthomas involving the Achilles tendon, soles, hands, knees, elbows, and is associated with the unusual involvement of the ear. S. Karger AG 2015-11-28 /pmc/articles/PMC4777906/ /pubmed/26955329 http://dx.doi.org/10.1159/000441711 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Published online: November, 2015 Bermudez, Eduardo B. Storey, Leslie Mayo, Sheila Simpson, Gregory An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears |
title | An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears |
title_full | An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears |
title_fullStr | An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears |
title_full_unstemmed | An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears |
title_short | An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears |
title_sort | unusual case of multiple tendinous xanthomas involving the extremities and the ears |
topic | Published online: November, 2015 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777906/ https://www.ncbi.nlm.nih.gov/pubmed/26955329 http://dx.doi.org/10.1159/000441711 |
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