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An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears

Tendinous and subcutaneous xanthomas are nodular deposits of lipid-filled macrophages, which commonly form on the Achilles tendon, hands, feet, elbows, and knees. These nodules are frequently associated with familial hyperlipidemia, a group of diseases involving impaired cholesterol metabolism, and...

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Detalles Bibliográficos
Autores principales: Bermudez, Eduardo B., Storey, Leslie, Mayo, Sheila, Simpson, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777906/
https://www.ncbi.nlm.nih.gov/pubmed/26955329
http://dx.doi.org/10.1159/000441711
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author Bermudez, Eduardo B.
Storey, Leslie
Mayo, Sheila
Simpson, Gregory
author_facet Bermudez, Eduardo B.
Storey, Leslie
Mayo, Sheila
Simpson, Gregory
author_sort Bermudez, Eduardo B.
collection PubMed
description Tendinous and subcutaneous xanthomas are nodular deposits of lipid-filled macrophages, which commonly form on the Achilles tendon, hands, feet, elbows, and knees. These nodules are frequently associated with familial hyperlipidemia, a group of diseases involving impaired cholesterol metabolism, and the accelerated development of atherosclerotic plaques. Since xanthomas may precede the diagnosis of hyperlipidemia, early identification can lead to preventative treatment that reduces the risk and morbidity of cardiovascular disease, including myocardial infarction. This case report presents a 43-year-old African-American male with multiple xanthomas involving the Achilles tendon, soles, hands, knees, elbows, and is associated with the unusual involvement of the ear.
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spelling pubmed-47779062016-03-07 An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears Bermudez, Eduardo B. Storey, Leslie Mayo, Sheila Simpson, Gregory Case Rep Dermatol Published online: November, 2015 Tendinous and subcutaneous xanthomas are nodular deposits of lipid-filled macrophages, which commonly form on the Achilles tendon, hands, feet, elbows, and knees. These nodules are frequently associated with familial hyperlipidemia, a group of diseases involving impaired cholesterol metabolism, and the accelerated development of atherosclerotic plaques. Since xanthomas may precede the diagnosis of hyperlipidemia, early identification can lead to preventative treatment that reduces the risk and morbidity of cardiovascular disease, including myocardial infarction. This case report presents a 43-year-old African-American male with multiple xanthomas involving the Achilles tendon, soles, hands, knees, elbows, and is associated with the unusual involvement of the ear. S. Karger AG 2015-11-28 /pmc/articles/PMC4777906/ /pubmed/26955329 http://dx.doi.org/10.1159/000441711 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Published online: November, 2015
Bermudez, Eduardo B.
Storey, Leslie
Mayo, Sheila
Simpson, Gregory
An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
title An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
title_full An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
title_fullStr An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
title_full_unstemmed An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
title_short An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the Ears
title_sort unusual case of multiple tendinous xanthomas involving the extremities and the ears
topic Published online: November, 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777906/
https://www.ncbi.nlm.nih.gov/pubmed/26955329
http://dx.doi.org/10.1159/000441711
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