Regulatory T Cells in Melanoma Revisited by a Computational Clustering of FOXP3(+) T Cell Subpopulations

CD4(+) T cells that express the transcription factor FOXP3 (FOXP3(+) T cells) are commonly regarded as immunosuppressive regulatory T cells (Tregs). FOXP3(+) T cells are reported to be increased in tumor-bearing patients or animals and are considered to suppress antitumor immunity, but the evidence...

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Detalles Bibliográficos
Autores principales: Fujii, Hiroko, Josse, Julie, Tanioka, Miki, Miyachi, Yoshiki, Husson, François, Ono, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Novel Immunological Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777917/
https://www.ncbi.nlm.nih.gov/pubmed/26864030
http://dx.doi.org/10.4049/jimmunol.1402695

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