Mechanism by which nuclear factor-kappa beta (NF-kB) regulates ovine fetal pulmonary vascular smooth muscle cell proliferation

Platelet activating factor (PAF) modulates ovine fetal pulmonary hemodynamic. PAF acts through its receptors (PAFR) in pulmonary vascular smooth muscle cells (PVSMC) to phosphorylate and induce nuclear translocation of NF-kB p65 leading to PVSMC proliferation. However, the interaction of NF-kB p65 a...

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Detalles Bibliográficos
Autores principales: Ogbozor, Uchenna D., Opene, Michael, Renteria, Lissette S., McBride, Shaemion, Ibe, Basil O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777924/
https://www.ncbi.nlm.nih.gov/pubmed/26966681
http://dx.doi.org/10.1016/j.ymgmr.2015.05.003

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