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An Evaluation of Active Learning Causal Discovery Methods for Reverse-Engineering Local Causal Pathways of Gene Regulation
Reverse-engineering of causal pathways that implicate diseases and vital cellular functions is a fundamental problem in biomedicine. Discovery of the local causal pathway of a target variable (that consists of its direct causes and direct effects) is essential for effective intervention and can faci...
Autores principales: | Ma, Sisi, Kemmeren, Patrick, Aliferis, Constantin F., Statnikov, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778024/ https://www.ncbi.nlm.nih.gov/pubmed/26939894 http://dx.doi.org/10.1038/srep22558 |
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