Macrophage Migration Inhibitory Factor (MIF) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation

Aging leads to unfavorable geometric and functional sequelae in the heart. The proinflammatory cytokine macrophage migration inhibitory factor (MIF) plays a role in the maintenance of cardiac homeostasis under stress conditions although its impact in cardiac aging remains elusive. This study was des...

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Detalles Bibliográficos
Autores principales: Xu, Xihui, Pang, Jiaojiao, Chen, Yuguo, Bucala, Richard, Zhang, Yingmei, Ren, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778027/
https://www.ncbi.nlm.nih.gov/pubmed/26940544
http://dx.doi.org/10.1038/srep22488

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