Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases

Hyper-aldosteronism is associated with myocardial dysfunction including induction of cardiac fibrosis and maladaptive hypertrophy. Mechanisms of these cardiotoxicities are not fully understood. Here we show that mineralocorticoid receptor (MR) activation by aldosterone leads to pathological myocardi...

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Detalles Bibliográficos
Autores principales: Cannavo, Alessandro, Liccardo, Daniela, Eguchi, Akito, Elliott, Katherine J., Traynham, Christopher J., Ibetti, Jessica, Eguchi, Satoru, Leosco, Dario, Ferrara, Nicola, Rengo, Giuseppe, Koch, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778065/
https://www.ncbi.nlm.nih.gov/pubmed/26932512
http://dx.doi.org/10.1038/ncomms10877

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