Effect of pioglitazone on the abrogated cardioprotective effect of ischemic preconditioning in hyperlipidemic rat heart

OBJECTIVES: The signaling pathways upstream of glycogen synthase kinase-3β (GSK-3β) get reduced during ischemic preconditioning (IPC) in hyperlipidemic rat heart. Pioglitazone, an insulin sensitizer, exerts cardioprotection through GSK-3β. The objective of the study is to investigate the role of pio...

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Detalles Bibliográficos
Autores principales: Mittal, Dhiraj, Taliyan, Rajeev, Sharma, P. L., Yadav, Harlokesh Narayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778209/
https://www.ncbi.nlm.nih.gov/pubmed/26997724
http://dx.doi.org/10.4103/0253-7613.174545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778209/
https://www.ncbi.nlm.nih.gov/pubmed/26997724
http://dx.doi.org/10.4103/0253-7613.174545

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