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Use of (18)F-2-Fluorodeoxyglucose to Label Antibody Fragments for Immuno-Positron Emission Tomography of Pancreatic Cancer
[Image: see text] We generated (18)F-labeled antibody fragments for positron emission tomography (PET) imaging using a sortase-mediated reaction to install a trans-cyclooctene-functionalized short peptide onto proteins of interest, followed by reaction with a tetrazine-labeled-(18)F-2-deoxyfluoroglu...
Autores principales: | Rashidian, Mohammad, Keliher, Edmund J., Dougan, Michael, Juras, Patrick K., Cavallari, Marco, Wojtkiewicz, Gregory R., Jacobsen, Johanne T., Edens, Jerre G., Tas, Jeroen M. J., Victora, Gabriel, Weissleder, Ralph, Ploegh, Hidde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778250/ https://www.ncbi.nlm.nih.gov/pubmed/26955657 http://dx.doi.org/10.1021/acscentsci.5b00121 |
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