A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models

BACKGROUND: One of the major issues in current pharmaceutical development is potential hepatotoxicity and drug-induced liver damage. This is due to the unique metabolic processes performed in the liver to prevent accumulation of a wide range of chemicals in the blood. Recently, we developed a physio...

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Detalles Bibliográficos
Autores principales: Rezania, Vahid, Coombe, Dennis, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778290/
https://www.ncbi.nlm.nih.gov/pubmed/26939615
http://dx.doi.org/10.1186/s12976-016-0034-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778290/
https://www.ncbi.nlm.nih.gov/pubmed/26939615
http://dx.doi.org/10.1186/s12976-016-0034-5

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