Cargando…
A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models
BACKGROUND: One of the major issues in current pharmaceutical development is potential hepatotoxicity and drug-induced liver damage. This is due to the unique metabolic processes performed in the liver to prevent accumulation of a wide range of chemicals in the blood. Recently, we developed a physio...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778290/ https://www.ncbi.nlm.nih.gov/pubmed/26939615 http://dx.doi.org/10.1186/s12976-016-0034-5 |