Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine

BACKGROUND: Primary diffuse leptomeningeal gliomatosis (PDLG) is a very rare neuro-oncological disease, with only 90 cases of PDLG described in medical literature so far. CASE PRESENTATION: We present a case report of a 56-years-old female patient, who was originally hospitalized due to cervical spi...

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Autores principales: Sivák, Štefan, Kantorová, Ema, Kurča, Egon, Marcinek, Juraj, Slávik, Pavol, Michalik, Jozef, Nosáľ, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778314/
https://www.ncbi.nlm.nih.gov/pubmed/26944049
http://dx.doi.org/10.1186/s12885-016-2224-2
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author Sivák, Štefan
Kantorová, Ema
Kurča, Egon
Marcinek, Juraj
Slávik, Pavol
Michalik, Jozef
Nosáľ, Vladimír
author_facet Sivák, Štefan
Kantorová, Ema
Kurča, Egon
Marcinek, Juraj
Slávik, Pavol
Michalik, Jozef
Nosáľ, Vladimír
author_sort Sivák, Štefan
collection PubMed
description BACKGROUND: Primary diffuse leptomeningeal gliomatosis (PDLG) is a very rare neuro-oncological disease, with only 90 cases of PDLG described in medical literature so far. CASE PRESENTATION: We present a case report of a 56-years-old female patient, who was originally hospitalized due to cervical spine pain lasting several months. Despite complex diagnostics and treatment, the neurological state of the patient progressively deteriorated. Patient died 10 months after the first reported symptom. Postmortem pathological findings resulted in the diagnosis of PDLG. CONCLUSIONS: Affection of the cervical spine in early stages of PDLG is rare and has been described in only six patients so far. PDLG is a fatal neuro-oncological disease and it must be kept in mind in the differential diagnosis of persistent back pain syndromes.
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spelling pubmed-47783142016-03-05 Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine Sivák, Štefan Kantorová, Ema Kurča, Egon Marcinek, Juraj Slávik, Pavol Michalik, Jozef Nosáľ, Vladimír BMC Cancer Case Report BACKGROUND: Primary diffuse leptomeningeal gliomatosis (PDLG) is a very rare neuro-oncological disease, with only 90 cases of PDLG described in medical literature so far. CASE PRESENTATION: We present a case report of a 56-years-old female patient, who was originally hospitalized due to cervical spine pain lasting several months. Despite complex diagnostics and treatment, the neurological state of the patient progressively deteriorated. Patient died 10 months after the first reported symptom. Postmortem pathological findings resulted in the diagnosis of PDLG. CONCLUSIONS: Affection of the cervical spine in early stages of PDLG is rare and has been described in only six patients so far. PDLG is a fatal neuro-oncological disease and it must be kept in mind in the differential diagnosis of persistent back pain syndromes. BioMed Central 2016-03-04 /pmc/articles/PMC4778314/ /pubmed/26944049 http://dx.doi.org/10.1186/s12885-016-2224-2 Text en © Sivák et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sivák, Štefan
Kantorová, Ema
Kurča, Egon
Marcinek, Juraj
Slávik, Pavol
Michalik, Jozef
Nosáľ, Vladimír
Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
title Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
title_full Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
title_fullStr Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
title_full_unstemmed Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
title_short Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
title_sort primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778314/
https://www.ncbi.nlm.nih.gov/pubmed/26944049
http://dx.doi.org/10.1186/s12885-016-2224-2
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