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Identification of mRNA isoform switching in breast cancer
BACKGROUND: Alternative splicing provides a major mechanism to generate protein diversity. Increasing evidence suggests a link of dysregulation of splicing associated with cancer. While previous genomic-based studies demonstrated the expression of a handful of tumor-specific isoforms, genome-wide al...
Autores principales: | Zhao, Wei, Hoadley, Katherine A., Parker, Joel S., Perou, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778320/ https://www.ncbi.nlm.nih.gov/pubmed/26939613 http://dx.doi.org/10.1186/s12864-016-2521-9 |
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