Buccal injection of synthetic HPV long peptide vaccine induces local and systemic antigen-specific CD8+ T-cell immune responses and antitumor effects without adjuvant

BACKGROUND: Human Papillomavirus is responsible for over 99 % of cervical cancers and is associated with cancers of the head and neck. The currently available prophylactic vaccines against HPV do not generate therapeutic effects against established HPV infections and associated lesions and disease....

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Detalles Bibliográficos
Autores principales: Yang, Ming-Chieh, Yang, Andrew, Qiu, Jin, Yang, Benjamin, He, Liangmei, Tsai, Ya-Chea, Jeang, Jessica, Wu, T.-C., Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778350/
https://www.ncbi.nlm.nih.gov/pubmed/26949512
http://dx.doi.org/10.1186/s13578-016-0083-9

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