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Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst
An asymmetric α-amination of β-keto esters with azodicarboxylate in the presence of a guanidine–bisurea bifunctional organocatalyst was investigated. The α-amination products were obtained in up to 99% yield with up to 94% ee.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778535/ https://www.ncbi.nlm.nih.gov/pubmed/26977179 http://dx.doi.org/10.3762/bjoc.12.22 |
| _version_ | 1782419484102885376 |
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| author | Odagi, Minami Yamamoto, Yoshiharu Nagasawa, Kazuo |
| author_facet | Odagi, Minami Yamamoto, Yoshiharu Nagasawa, Kazuo |
| author_sort | Odagi, Minami |
| collection | PubMed |
| description | An asymmetric α-amination of β-keto esters with azodicarboxylate in the presence of a guanidine–bisurea bifunctional organocatalyst was investigated. The α-amination products were obtained in up to 99% yield with up to 94% ee. |
| format | Online Article Text |
| id | pubmed-4778535 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-47785352016-03-14 Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst Odagi, Minami Yamamoto, Yoshiharu Nagasawa, Kazuo Beilstein J Org Chem Full Research Paper An asymmetric α-amination of β-keto esters with azodicarboxylate in the presence of a guanidine–bisurea bifunctional organocatalyst was investigated. The α-amination products were obtained in up to 99% yield with up to 94% ee. Beilstein-Institut 2016-02-04 /pmc/articles/PMC4778535/ /pubmed/26977179 http://dx.doi.org/10.3762/bjoc.12.22 Text en Copyright © 2016, Odagi et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Odagi, Minami Yamamoto, Yoshiharu Nagasawa, Kazuo Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| title | Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| title_full | Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| title_fullStr | Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| title_full_unstemmed | Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| title_short | Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| title_sort | asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778535/ https://www.ncbi.nlm.nih.gov/pubmed/26977179 http://dx.doi.org/10.3762/bjoc.12.22 |
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