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Asymmetric α-amination of β-keto esters using a guanidine–bisurea bifunctional organocatalyst
An asymmetric α-amination of β-keto esters with azodicarboxylate in the presence of a guanidine–bisurea bifunctional organocatalyst was investigated. The α-amination products were obtained in up to 99% yield with up to 94% ee.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778535/ https://www.ncbi.nlm.nih.gov/pubmed/26977179 http://dx.doi.org/10.3762/bjoc.12.22 |