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Autoimmune disease-associated gene expression is reduced by BET-inhibition

For many autoimmune diseases, the underlying mechanism is still unknown. In order to get more insight into the etiology of autoimmune diseases, we recently published a study were we performed epigenetic profiling and RNA sequencing on CD4(+)CD45RO(+) T cells derived from the site of inflammation of...

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Detalles Bibliográficos
Autores principales: Peeters, Janneke G.C., Vervoort, Stephin J., Mijnheer, Gerdien, de Roock, Sytze, Vastert, Sebastiaan J., Nieuwenhuis, Edward E.S., van Wijk, Femke, Prakken, Berent J., Mokry, Michal, van Loosdregt, Jorg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778599/
https://www.ncbi.nlm.nih.gov/pubmed/26981351
http://dx.doi.org/10.1016/j.gdata.2015.11.004