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Genome Sequencing and Annotation of Mycobacterium tuberculosis PR08 strain

Mycobacterium tuberculosis is an acid fast bacterial species in the family Mycobacteriaceae and is the causative agent of most cases of tuberculosis. Here, we report the genomic features of Mycobacterium tuberculosis isolated from the cerebrospinal fluid (CSF) of a patient diagnosed with both pulmon...

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Detalles Bibliográficos
Autores principales: Jaafar, Mohammad Maaruf, Halim, Mohd Zakihalani A., Ismail, Mohamad Izwan, Shien, Lee Lian, Kek, Teh Lay, Fong, Ngeow Yun, Nor, Norazmi Mohd, Zainuddin, Zainul Fadziruddin, Hock, Tang Thean, Najimudin, Mohd Nazalan Mohd, Salleh, Mohd Zaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778648/
https://www.ncbi.nlm.nih.gov/pubmed/26981383
http://dx.doi.org/10.1016/j.gdata.2015.12.030
Descripción
Sumario:Mycobacterium tuberculosis is an acid fast bacterial species in the family Mycobacteriaceae and is the causative agent of most cases of tuberculosis. Here, we report the genomic features of Mycobacterium tuberculosis isolated from the cerebrospinal fluid (CSF) of a patient diagnosed with both pulmonary and extrapulmonary tuberculosis (TB). The isolated strain was identified as Mycobacterium tuberculosis PR08 (MTB PR08). Genomic DNA of the MTB PR08 strain was extracted and subjected to whole genome sequencing using MiSeq (Illumina, CA,USA). The draft genome size of MTB PR08 strain is 4,292,364 bp with a G + C content of 65.2%. This strain was annotated to have 4723 genes and 48 RNAs. This whole genome shotgun project has been deposited at DDBJ/EMBL/GenBank under the accession number CP010895.