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Gene expression profiling of human calcific aortic valve disease

Calcific aortic valve disease is a slowly progressive disorder that ranges from mild valve thickening (i.e. aortic sclerosis) to severe calcification of valves (i.e. aortic stenosis). Gene expression profiling analysis of non-calcified controls, sclerotic, and calcified aortic valves was performed t...

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Detalles Bibliográficos
Autor principal: Rysä, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778651/
https://www.ncbi.nlm.nih.gov/pubmed/26981379
http://dx.doi.org/10.1016/j.gdata.2015.12.015
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author Rysä, Jaana
author_facet Rysä, Jaana
author_sort Rysä, Jaana
collection PubMed
description Calcific aortic valve disease is a slowly progressive disorder that ranges from mild valve thickening (i.e. aortic sclerosis) to severe calcification of valves (i.e. aortic stenosis). Gene expression profiling analysis of non-calcified controls, sclerotic, and calcified aortic valves was performed to better understand the progression of calcific aortic valve disease. The complementary information related to processing and statistical analysis of the DNA microarray data is provided in this article. Interpretation of this data can be found in a research article entitled “MicroRNA-125b and chemokine CCL4 expression are associated with calcific aortic valve disease” [1]. The microarray data complies with MIAME guidelines and is deposited in the Gene Expression Omnibus (GEO) database under accession number GSE51472.
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spelling pubmed-47786512016-03-15 Gene expression profiling of human calcific aortic valve disease Rysä, Jaana Genom Data Data in Brief Calcific aortic valve disease is a slowly progressive disorder that ranges from mild valve thickening (i.e. aortic sclerosis) to severe calcification of valves (i.e. aortic stenosis). Gene expression profiling analysis of non-calcified controls, sclerotic, and calcified aortic valves was performed to better understand the progression of calcific aortic valve disease. The complementary information related to processing and statistical analysis of the DNA microarray data is provided in this article. Interpretation of this data can be found in a research article entitled “MicroRNA-125b and chemokine CCL4 expression are associated with calcific aortic valve disease” [1]. The microarray data complies with MIAME guidelines and is deposited in the Gene Expression Omnibus (GEO) database under accession number GSE51472. Elsevier 2015-12-19 /pmc/articles/PMC4778651/ /pubmed/26981379 http://dx.doi.org/10.1016/j.gdata.2015.12.015 Text en © 2015 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data in Brief
Rysä, Jaana
Gene expression profiling of human calcific aortic valve disease
title Gene expression profiling of human calcific aortic valve disease
title_full Gene expression profiling of human calcific aortic valve disease
title_fullStr Gene expression profiling of human calcific aortic valve disease
title_full_unstemmed Gene expression profiling of human calcific aortic valve disease
title_short Gene expression profiling of human calcific aortic valve disease
title_sort gene expression profiling of human calcific aortic valve disease
topic Data in Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778651/
https://www.ncbi.nlm.nih.gov/pubmed/26981379
http://dx.doi.org/10.1016/j.gdata.2015.12.015
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