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mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration

Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function mutations affecting the gene encoding the dystrophin protein. While the primary genetic insult in DMD is well described, many details of the molecular and cellular pathologies t...

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Detalles Bibliográficos
Autores principales: Roberts, Thomas C., Blomberg, K. Emelie M., Smith, C.I. Edvard, EL Andaloussi, Samir, Wood, Matthew J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778658/
https://www.ncbi.nlm.nih.gov/pubmed/26981371
http://dx.doi.org/10.1016/j.gdata.2015.11.025

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