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mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration
Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function mutations affecting the gene encoding the dystrophin protein. While the primary genetic insult in DMD is well described, many details of the molecular and cellular pathologies t...
Autores principales: | Roberts, Thomas C., Blomberg, K. Emelie M., Smith, C.I. Edvard, EL Andaloussi, Samir, Wood, Matthew J.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778658/ https://www.ncbi.nlm.nih.gov/pubmed/26981371 http://dx.doi.org/10.1016/j.gdata.2015.11.025 |
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