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Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II
The transition of RNA polymerase II (Pol II) from transcription initiation into productive elongation in eukaryotic cells is regulated by the P-TEFb kinase, which phosphorylates the C-terminal domain of paused Pol II at promoter-proximal regions. Our recent study found that P-TEFb (in an inhibited s...
Autores principales: | McNamara, Ryan P., Guzman, Carlos, Reeder, Jonathan E., D'Orso, Iván |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778668/ https://www.ncbi.nlm.nih.gov/pubmed/26981421 http://dx.doi.org/10.1016/j.gdata.2016.01.019 |
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