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Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II

The transition of RNA polymerase II (Pol II) from transcription initiation into productive elongation in eukaryotic cells is regulated by the P-TEFb kinase, which phosphorylates the C-terminal domain of paused Pol II at promoter-proximal regions. Our recent study found that P-TEFb (in an inhibited s...

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Detalles Bibliográficos
Autores principales: McNamara, Ryan P., Guzman, Carlos, Reeder, Jonathan E., D'Orso, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778668/
https://www.ncbi.nlm.nih.gov/pubmed/26981421
http://dx.doi.org/10.1016/j.gdata.2016.01.019

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