Conditional Inducible Triple-Transgenic Mouse Model for Rapid Real-Time Detection of HCV NS3/4A Protease Activity

Hepatitis C virus (HCV) frequently establishes persistent infections that can develop into severe liver disease. The HCV NS3/4A serine protease is not only essential for viral replication but also cleaves multiple cellular targets that block downstream interferon activation. Therefore, NS3/4A is an...

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Detalles Bibliográficos
Autores principales: Yao, Min, Lu, Xin, Lei, Yingfeng, Yang, Jing, Zhao, Haiwei, Qiao, Qinghua, Han, Peijun, Xu, Zhikai, Yin, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778798/
https://www.ncbi.nlm.nih.gov/pubmed/26943641
http://dx.doi.org/10.1371/journal.pone.0150894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778798/
https://www.ncbi.nlm.nih.gov/pubmed/26943641
http://dx.doi.org/10.1371/journal.pone.0150894

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