Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models

Although genome-wide association studies (GWASs) have discovered numerous novel genetic variants associated with many complex traits and diseases, those genetic variants typically explain only a small fraction of phenotypic variance. Factors that account for phenotypic variance include environmental...

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Detalles Bibliográficos
Autores principales: Sul, Jae Hoon, Bilow, Michael, Yang, Wen-Yun, Kostem, Emrah, Furlotte, Nick, He, Dan, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778803/
https://www.ncbi.nlm.nih.gov/pubmed/26943367
http://dx.doi.org/10.1371/journal.pgen.1005849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778803/
https://www.ncbi.nlm.nih.gov/pubmed/26943367
http://dx.doi.org/10.1371/journal.pgen.1005849

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