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Identification of a Short Cell-Penetrating Peptide from Bovine Lactoferricin for Intracellular Delivery of DNA in Human A549 Cells

Cell-penetrating peptides (CPPs) have been shown to deliver cargos, including protein, DNA, RNA, and nanomaterials, in fully active forms into live cells. Most of the CPP sequences in use today are based on non-native proteins that may be immunogenic. Here we demonstrate that the L5a CPP (RRWQW) fro...

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Detalles Bibliográficos
Autores principales: Liu, Betty R., Huang, Yue-Wern, Aronstam, Robert S., Lee, Han-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778846/
https://www.ncbi.nlm.nih.gov/pubmed/26942714
http://dx.doi.org/10.1371/journal.pone.0150439