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High Throughput Sequencing Identifies Misregulated Genes in the Drosophila Polypyrimidine Tract-Binding Protein (hephaestus) Mutant Defective in Spermatogenesis

The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during spermatogenesis. The heph(2) mutation in this gene results in a specific defect in spermatogenesis, causing aberrant spermatid individualization and male sterility. However, the array of molecula...

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Detalles Bibliográficos
Autores principales: Sridharan, Vinod, Heimiller, Joseph, Robida, Mark D., Singh, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778870/
https://www.ncbi.nlm.nih.gov/pubmed/26942929
http://dx.doi.org/10.1371/journal.pone.0150768