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Contrasting Roles of Islet Resident Immunoregulatory Macrophages and Dendritic Cells in Experimental Autoimmune Type 1 Diabetes

The innate immune system critically shapes diabetogenic adaptive immunity during type 1 diabetes (T1D) pathogenesis. While the role of tissue-infiltrating monocyte-derived macrophages in T1D is well established, the role of their tissue-resident counterparts remains undefined. We now demonstrate tha...

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Detalles Bibliográficos
Autores principales: Thornley, Thomas B., Agarwal, Krishna A., Kyriazis, Periklis, Ma, Lingzhi, Chipashvili, Vaja, Aker, Jonathan E., Korniotis, Sarantis, Csizmadia, Eva, Strom, Terry B., Koulmanda, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778921/
https://www.ncbi.nlm.nih.gov/pubmed/26943809
http://dx.doi.org/10.1371/journal.pone.0150792