Polymorphisms in Plasmodium vivax Circumsporozoite Protein (CSP) Influence Parasite Burden and Cytokine Balance in a Pre-Amazon Endemic Area from Brazil

Mechanisms involved in severe P. vivax malaria remain unclear. Parasite polymorphisms, parasite load and host cytokine profile may influence the course of infection. In this study, we investigated the influence of circumsporozoite protein (CSP) polymorphisms on parasite load and cytokine profile in...

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Detalles Bibliográficos
Autores principales: Ribeiro, Bruno de Paulo, Cassiano, Gustavo Capatti, de Souza, Rodrigo Medeiros, Cysne, Dalila Nunes, Grisotto, Marcos Augusto Grigolin, de Azevedo dos Santos, Ana Paula Silva, Marinho, Cláudio Romero Farias, Machado, Ricardo Luiz Dantas, Nascimento, Flávia Raquel Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778932/
https://www.ncbi.nlm.nih.gov/pubmed/26943639
http://dx.doi.org/10.1371/journal.pntd.0004479

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