IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice

Endothelial cells (EC) are the main target for Orientia tsutsugamushi infection and EC dysfunction is a hallmark of severe scrub typhus in patients. However, the molecular basis of EC dysfunction and its impact on infection outcome are poorly understood. We found that C57BL/6 mice that received a le...

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Detalles Bibliográficos
Autores principales: Shelite, Thomas R., Liang, Yuejin, Wang, Hui, Mendell, Nicole L., Trent, Brandon J., Sun, Jiaren, Gong, Bin, Xu, Guang, Hu, Haitao, Bouyer, Donald H., Soong, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778942/
https://www.ncbi.nlm.nih.gov/pubmed/26943125
http://dx.doi.org/10.1371/journal.pntd.0004467

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