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T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium

An emerging concept of normal brain immune surveillance proposes that recently and moderately activated central memory T lymphocytes enter the central nervous system (CNS) directly into the cerebrospinal fluid (CSF) via the choroid plexus. Within the CSF space, T cells inspect the CNS environment fo...

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Detalles Bibliográficos
Autores principales: Strazielle, Nathalie, Creidy, Rita, Malcus, Christophe, Boucraut, José, Ghersi-Egea, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778949/
https://www.ncbi.nlm.nih.gov/pubmed/26942913
http://dx.doi.org/10.1371/journal.pone.0150945