Post splenectomy related pulmonary hypertension

Splenectomy predisposes patients to a slew of infectious and non-infectious complications including pulmonary vascular disease. Patients are at increased risk for venous thromboembolic events due to various mechanisms that may lead to chronic thromboembolic pulmonary hypertension (CTEPH). The develo...

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Autores principales: Palkar, Atul V, Agrawal, Abhinav, Verma, Sameer, Iftikhar, Asma, Miller, Edmund J, Talwar, Arunabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778975/
https://www.ncbi.nlm.nih.gov/pubmed/26949600
http://dx.doi.org/10.5320/wjr.v5.i2.69
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author Palkar, Atul V
Agrawal, Abhinav
Verma, Sameer
Iftikhar, Asma
Miller, Edmund J
Talwar, Arunabh
author_facet Palkar, Atul V
Agrawal, Abhinav
Verma, Sameer
Iftikhar, Asma
Miller, Edmund J
Talwar, Arunabh
author_sort Palkar, Atul V
collection PubMed
description Splenectomy predisposes patients to a slew of infectious and non-infectious complications including pulmonary vascular disease. Patients are at increased risk for venous thromboembolic events due to various mechanisms that may lead to chronic thromboembolic pulmonary hypertension (CTEPH). The development of CTEPH and pulmonary vasculopathy after splenectomy involves complex pathophysiologic mechanisms, some of which remain unclear. This review attempts congregate the current evidence behind our understanding about the etio-pathogenesis of pulmonary vascular disease related to splenectomy and highlight the controversies that surround its management.
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spelling pubmed-47789752016-03-04 Post splenectomy related pulmonary hypertension Palkar, Atul V Agrawal, Abhinav Verma, Sameer Iftikhar, Asma Miller, Edmund J Talwar, Arunabh World J Respirol Article Splenectomy predisposes patients to a slew of infectious and non-infectious complications including pulmonary vascular disease. Patients are at increased risk for venous thromboembolic events due to various mechanisms that may lead to chronic thromboembolic pulmonary hypertension (CTEPH). The development of CTEPH and pulmonary vasculopathy after splenectomy involves complex pathophysiologic mechanisms, some of which remain unclear. This review attempts congregate the current evidence behind our understanding about the etio-pathogenesis of pulmonary vascular disease related to splenectomy and highlight the controversies that surround its management. 2015-07-28 2015-07-28 /pmc/articles/PMC4778975/ /pubmed/26949600 http://dx.doi.org/10.5320/wjr.v5.i2.69 Text en Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Article
Palkar, Atul V
Agrawal, Abhinav
Verma, Sameer
Iftikhar, Asma
Miller, Edmund J
Talwar, Arunabh
Post splenectomy related pulmonary hypertension
title Post splenectomy related pulmonary hypertension
title_full Post splenectomy related pulmonary hypertension
title_fullStr Post splenectomy related pulmonary hypertension
title_full_unstemmed Post splenectomy related pulmonary hypertension
title_short Post splenectomy related pulmonary hypertension
title_sort post splenectomy related pulmonary hypertension
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778975/
https://www.ncbi.nlm.nih.gov/pubmed/26949600
http://dx.doi.org/10.5320/wjr.v5.i2.69
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